Union Baptist Church is affiliated with the following organizations:

• Eastern Community Church Fellowship
• Interdenominational Ministerial Alliance of Durham and Vicinity
• Durham County Missionary Union
• Durham County Youth Missionary Union
• Fifth District Sunday School Convention
• East Cedar Grove Missionary Baptist Association
• General Baptist State Convention of North Carolina, Inc.
• Woman's Baptist Home & Foreign Missions Convention of North Carolina
• Lott Carey Foreign Missions Convention
• Progressive National Baptist Convention
• American Baptist Churches of the South
• American Baptist Churches/USA